Dr Zainuddin

Ir (Phys Chem), MSc (Polym Chem), PhD (Polym Chem)

Research Scientist

Contact Zainuddin

Room: Student & Fellowship Office
Phone: +61 7 3010 3381 (office) 3380 (lab)
Fax: +61 7 3010 3390

E-mail: ;

Biography

Zainuddin is currently working in Queensland Eye Institute (QEI) with Adjunct Professor Traian V. Chirila to develop cell-supporting materials and other research projectcs listed below. He holds positions of an adjunct senior lecturer with the school of medicine and a visiting scientist with the centre for magnetic resonance, the University of Queensland. He earned his PhD degree from the University of Queensland in 2005, working in the laboratory of Professor David J.T. Hill and Professor Andrew K. Whittaker. He stayed as a postdoctoral fellow in the same laboratory for nearly one year. His MSc degree was obtained from the Technical University of Lodz (Poland) in 1993, working in the laboratory of Professor Janusz M. Rosiak. After he completed his Engineer (Ir) degree at the University of Gadjah Mada (Indonesia) in 1988, he then worked with the Indonesian National Atomic Energy Agency (BATAN) for over 10 years to develop polymeric biomaterials using radiation techniques. During his service to this Agency he has established a pilot-scale production of hydrogel wound dressings. Also, in 1990 and 1997 he spent more than one year as a visiting researcher in the laboratory of Dr. Keizo Makuuchi and Dr. Fumio Yoshii at Takasaki Radiation Chemistry Research Establishment, Japan Atomic Energy Research Institute to develop heat resistant PVA hydrogels and biodegradable polymer blends. He has been awarded two research fellowships by International Atomic Energy Agency (IAEA) to visit Poland (1992-1993) and Australia (1999), respectively. His research to date has brought over 30 international publications and 14 contributions to international scientific meetings.

Current Research Interests & Projects

• Synthesis of visible-light photoinitiators for crosslinking of corneal stromal collagen
• Assembling synthetic hydrogels and fibrous proteins for tissue engineering applications
• Novel photocrosslinkable tissue adhesives
• Modification of polymers (grafting, copolymerisation, blending, IPN/semi-IPN and laser ablation)
• Calcification of polymeric hydrogels and its prevention
• Utilization of radiation techniques for biomaterials development 

Selected Publications

Ghassemifar R, Redmond S, Zainuddin and Chirila TV. Advancing towards a tissue-engineered tympanic membrane: Silk fibroin as a substratum for growing human eardrum keratinocytes, J Biomater Appl, Online First, 22 April 2009 (doi:10.1177/0885328209104289).

Zainuddin, Le TT, Park Y, Chirila TV, Halley PJ, Whittaker AK. The behaviour of aged regenerated Bombyx mori silk fibroin solutions studied by 1H NMR and rheology. Biomaterials, 29 (2008) 4268-4274.

Zainuddin, Barnard Z, Keen I, Hill DJT, Chirila TV, Harkin DG. PHEMA Hydrogels modified through the grafting of phosphate groups by ATRP support the attachment and growth of human corneal epithelial cells. J Biomater Appl, 23 (2008) 147-168.

Chirila TV, Barnard Z, Zainuddin, Harkin DG, Schwab IR, Hirst LW. Bombyx mori silk fibroin membranes as potential substrata for epithelial constructs used in the management of ocular surface disorders. Tissue Eng, 14 (2008) 1203-1211.

Zainuddin, Hill DJT, Whittaker AK, Kemp A, Chirila TV. Effect of citrate anions on prevention of calcification of PHEMA hydrogels. In: Polymer durability and radiation effects, Polymer property changes. Celina MC and Assink RA, eds., ACS Symp. Ser.978, ACS, Washington, DC (2008), Chapter 25, p.301-316.

Zainuddin, Hill DJT, Whittaker AK. Mineralization of radiation-crosslinked PVA/PVP hydrogels. J Biomed Mater Res A, 83 (2007) 354-361.

Zainuddin, Hill DJT, Whittaker AK, Chirila TV. In-vitro study of the spontaneous calcification of PHEMA-based hydrogels in simulated body fluid. J Mater Sci Mater Med, 17 (2006) 1245-1254.

Zainuddin, Chirila TV, Hill D J T, Whittaker AK. Study of the calcification of PHEMA hydrogels using a two compartment permeation cell. J Mol Struct, 739 (2005) 199-206.

Zainuddin, Cooper-White JJ, Hill DJT. Viscoelasticity of radiation-formed PVA/PVP hydrogel. J Biomater Sci Polym Edn, 13 (2002) 1007-1020.

Razzak MT, Darwis D, Zainuddin, Sukirno. Irradiation of polyvinyl alcohol and polyvinyl pyrrolidone blended hydrogel for wound dressing. Rad Phys Chem, 62(1) (2001) 107-113.

Zainuddin, Razzak MT, Yoshii F, Makuuchi K. Radiation effect on the mechanical stability and biodegradability of CPP/Bionolle blend, Polym Degrad Stab, 63(2) (1999) 311-320.

Ulanski P, Zainuddin, Rosiak JM. Pulse radiolysis of poly(ethylene oxide) in aqueous solution. I. Formation of macroradicals, Radiat Phys Chem, 46(4-60) (1995) 913-916.